The Fourth International MELODI Workshop was organized by STUK – Radiation and Nuclear Safety Authority in Helsinki, Finland, on 12-14 September 2012.
The workshop offered an update of recent low-dose research issues, and an opportunity to participate in the MELODI Low Dose Research Platform, a major step in the long term goals that the European Low-Dose Risk research intends to achieve.
Publication of the 4th MELODI Workshop
Sisko Salomaa, Kevin M Prise, Michael J Atkinson, Andrzej Wojcik, Anssi Auvinen, Bernd Grosche, Laure Sabatier, Jean-René Jourdain, Eeva Salminen, Sarah Baatout, Ulrike Kulka, Hans Rabus, Eric Blanchardon, Dietrich Averbeck and Wolfgang Weiss
The fourth workshop of the Multidisciplinary European Low Dose Initiative (MELODI) was organised by STUK—Radiation and Nuclear Safety Authority of Finland. It took place from 12 to 14 September 2012 in Helsinki, Finland. The meeting was attended by 179 scientists and professionals engaged in radiation research and radiation protection. We summarise the major scientific findings of the workshop and the recommendations for updating the MELODI Strategic Research Agenda and Road Map for future low dose research activities.
Presentations of the 4th MELODI Workshop
Tuesday 11 September 2012
Satellite event: DoReMi/MELODI Forum:
Education and Training for low dose risk research
Welcome and introduction to the Forum
Andrea Ottolenghi, Vere Smyth
THEME 1: EUROPEAN FRAMEWORK FOR SUPPORT OF E&T
E&T initiatives in other EURATOM platforms:
European Radioecology Alliance
EURATOM E&T approach for radiation protection
THEME 2: STRUCTURE AND INTEGRATION FOR E&T IN LOW-DOSE RESEARCH
Whom should we educate and train? Future careers of MSc radiobiology students
The planned new MSc course in radiation sciences in Munich
ECTS and ERASMUS MUNDUS
4th International MELODI Workshop
Wednesday, 12 September
Day theme: “Low dose risk research – state of the art”
Chair Sisko Salomaa
STUK – Tero Varjoranta
Ministry of Social Affairs and Health – Jari Keinänen
MELODI – Jacques Repussard
UNSCEAR – Wolfgang Weiss
ICRP – William F. Morgan
WHO – Maria del Rosario Perez
How MELODI can contribute to Horizon 2020
MELODI activities and the Strategic Research Agenda (SRA)
Plenary session: Epidemiology
Chairs: Peter Jacob and Anssi Auvinen
Epidemiological studies on natural radiation and cancer risk
Plenary session: Dose uncertainties
Chairs: Wolfgang Weiss and Maarit Muikku
Uncertainties in internal dose assessment
For the posters/corresponding slides presented during break-out sessions, see Poster section.
Thursday, 13 September
Day theme: “Emerging scientific challenges”
Plenary session: Epigenetics and Systems Biology
Chairs: Mats Harms-Ringdahl and Virpi Launonen
Epigenetic changes after radiation exposure
Plenary session: Biomarkers
Chairs: Michael Atkinson and Carita Lindholm
Molecular markers in radiation-induced thyroid cancer
Horst Zitzelsberger (presented by Kristian Unger)
Plenary lecture: Stem cells
Chairs: Simon Bouffler and Eeva Salminen
Effects of low-dose ionizing radiation on stem cells (not publishable)
Reports from break-out session 1
Group A: Epidemiological approaches
Group B: Cancer mechanisms and models
Group C: Infrastructure and knowledge management
For the posters/corresponding slides presented during break-out sessions, see Posters section.
Friday, 14 September
Day theme: “Integrating the research”
Reports from breakout session 2 and T&E Forum
Group A: Biomarkers and biobanks
Group B: Non-cancer effects
Group C: Low dose dosimetry and dose concept
Report from T&E Forum (11 September)
MELODI Award Ceremony
MELODI Award speech: Integrative Radiation Biology
Highlights of Euratom projects
Chairs: Katerina Ptackova and Géza Sáfrány
SOLO: Highlights of progress to date
DoReMi: Radiation induced premature senescence in endothelial cells, a system biology approach
EpiRadBio: Colon cancer risk among a-bomb survivors from multi-model inference with descriptive and mechanistic models (not publishable)
From CARDIORISK to PROCARDIO
Klaus Trott (presented by Michael Atkinson)
Satellite event: Training event by MELODI and Finnish Doctoral Programme in Environmental Health
UNSCEAR, BEIR VII and ICRP risk models and new developments
Radiation risk models for breast cancer
Estimation of radiation risk of lung cancer
Risk models for radiation-induced leukaemia
Book of Abstracts
View Book of abstracts HERE.
Posters of the 4th MELODI Workshop
E-posters/corresponding slides available (publication subject to approval of presenter):
1A: Epidemiological approaches
1B: Cancer mechanisms and models
1C: Infrastructures and knowledge management
The PTB microbeam facility by Giesen et al.
RENEB – Realizing the European Network of Biological Dosimetry by Kulka et al.
2A: Biomarkers and biobanks
EU EPI-CT project: biomarkers of radiation sensitivity for children by El-Saghire et al.
2B: Non-cancer effects
2C: Low dose dosimetry and dose concept
Cellular dosimetry of Sr-90 using Monte Carlo code MCNPX by Hocine et al.
A novel approach for assessing organ doses from paediatric CT scans in EPI-CT by Thierry-Chef et al.
Other low dose risk research (overall theme)
View Programme HERE.
View Programme ouline HERE.
DoReMi - MELODI T&E Forum
View Programme ouline HERE.
Fourth MELODI Workshop - Award
Dr. Kristian Unger has received the first MELODI Award dedicated to young scientists working on the effects of low dose ionising radiation. Dr. Unger is engaged in research in the field of bioinformatics and integrative biology in HelmholtzZentrum München. He will receive the Award certificate during the 4th MELODI workshop in Helsinki in September 14th.
MELODI-2012 Workshop Announcement
The Fourth International MELODI Workshop (www.melodi2012.org) is organized by STUK – Radiation and Nuclear Safety Authority in Helsinki, Finland, on 12-14 September 2012.
The workshop offers an update of recent low-dose research issues, and an opportunity to participate in the MELODI Low Dose Research Platform, a major step in the long term goals that the European Low-Dose Risk research intends to achieve. The main goal of MELODI (http://www.melodi-online.eu/) is to develop and maintain a Strategic Research Agenda (SRA) in the field of low-dose radiation research, and to actively promote its implementation. DoReMi Network of Excellence funded by the European Commission is supporting the setting up of the Platform and addressing some of its research needs (www.doremi-noe.net).
In line with one of the main SRA goals, a major aim of the workshop will be to set all topics in an interdisciplinary context. The environment of the workshop will provide to the attendants the possibility to actively participate in the discussion about the next steps for implementing the SRA.
The Workshop features plenary lectures, topical discussions in breakout sessions as well as poster contributions. The theme of the first day “Low dose risk research – state of the art” provides an introduction to the MELODI activities and the SRA and an update on recent epidemiological studies and dosimetric aspects of low dose studies. Potential implications of cardiovascular disease risk for radiation protection will be addressed. Followed by invited comments, discussion on the state-of- the art of MELODI SRA will follow in three break-out groups; the outcome will be reported the following day. The second day “Emerging scientific challenges” will feature the development of science and novel technologies, covering topics such as epigenetics, systems biology, stem cells and biomarkers that could be potentially used in molecular epidemiological studies. Three breakout sessions will be exploring the roadmap for future research, providing their reports on the final day. The third day “Integrating the research” will provide highlights of Euratom projects dedicated for research on low dose risk.
The attendants are encouraged to submit posters (abstract as well as a PDF of the full poster; paper poster as optional). Electronic posters will be available at the workshop web site. The electronic posters are seen as an important input to the discussions in the breakout sessions.
The full Workshop program will be duly posted together with the practical arrangements for registration, abstract submission, electronic poster preparation and accommodation. The maximum number of participants is 200. No registration fee is requested.
The MELODI Workshop will be preceded, on September 11, by a joint DoReMi-MELODI Forum on Training and Education. The focus of this Forum will be an exploration of ways for educational institutions to network in order to share course modules and students for the sake of making better use of European resources and providing more complete coverage of topics. A separate registration is requested. The maximum number of participants is 60.